Epilepsy South Africa, established in 1967 when it was known as the South African National Epilepsy League (SANEL), is a non-profit organisation and sole national organisation within the country which provides comprehensive and specialised services to those affected by epilepsy and other disabilities.

The organisation is dedicated to improving the lives our their target group, as well as to South Africans with intellectual disabilities, hydrocephalus and speech impairments. Epilepsy SA has a National Office located in Cape Town, as well as 6 other regional branches across the rest of the country.

The mission of the organisation is to promote human rights and a society for those living with disabilities, particularly people with epilepsy.